Symbol
Name
ID

Vdr
vitamin D (1,25-dihydroxyvitamin D3) receptor
MGI:103076

Phenotype annotations related to endocrine/exocrine glands

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Diabetes mellitus

Type II diabetes mellitus

Elevated circulating parathyroid hormone level

Increased circulating free T3

Increased circulating free T4 concentration

Decreased thyroid-stimulating hormone level

Primary hyperparathyroidism

Secondary hyperparathyroidism

Abnormality of the thyroid gland

Goiter

Graves disease

Delayed puberty

Disease(s) Associated with VDR

coronary artery disease

Fabry disease

Graves' disease

primary biliary cholangitis

primary hyperparathyroidism

vitamin D-dependent rickets type 2A

Mouse Phenotypes		abnormal large intestine crypts of Lieberkuhn morphology	endocrine/exocrine gland phenotype	enlarged parathyroid gland	increased thymus weight	thymus hyperplasia	absent mature ovarian follicles	dilated seminiferous tubule	increased testis weight	increased activity of parathyroid
Availability	Mouse Genotype	abnormal large intestine crypts of Lieberkuhn morphology	endocrine/exocrine gland phenotype	enlarged parathyroid gland	increased thymus weight	thymus hyperplasia	absent mature ovarian follicles	dilated seminiferous tubule	increased testis weight	increased activity of parathyroid
	Vdr^tm1.2Sgcg/Vdr^tm1.2Sgcg
	Vdr^tm1Mbd/Vdr^tm1Mbd
	Vdr^tm1Rge/Vdr^tm1Rge
	Vdr^tm1Ska/Vdr^tm1Ska
	Vdr^tm2.1Ska/Vdr^tm2.1Ska
	Vdr^tm1.1Sgcg/Vdr^tm1.2Sgcg Myl2^tm1(cre)Krc/Myl2⁺ (conditional)		*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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